Histone H2B type 1-L (H2BC13)

About Histone H2B type 1-L

Histone H2B type 1-L (H2BC13) is a protein from Homo sapiens identified by UniProt accession Q99880, 126 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.

Target properties

Protein name	Histone H2B type 1-L
UniProt accession	Q99880
Gene	H2BC13
Organism	Homo sapiens
Length	126 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (86)

Diseases linked to this target (Open Targets).

infectious disease · score 0.50
viral disease · score 0.50
breast carcinoma · score 0.39
melanoma · score 0.37
cancer · score 0.37
forced expiratory volume · score 0.21
unipolar depression · score 0.16
schizophrenia · score 0.16
serum albumin measurement · score 0.14
mean corpuscular volume · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q99880-F1	alphafold	PREDICTED	87.63	—

Amino-acid sequence (126 residues)

MPELAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSV YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIASEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT KYTSSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards