About Opiorphin prepropeptide
Opiorphin prepropeptide (OPRPN) is a protein
from Homo sapiens identified by UniProt accession
Q99935, 248 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Opiorphin prepropeptide |
|---|
| UniProt accession | Q99935 |
|---|
| Gene | OPRPN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- FEV change measurement · score 0.37
- lean body mass · score 0.10
- neoplasm · score 0.09
- breast carcinoma · score 0.05
- acanthosis nigricans · score 0.03
- psoriasis · score 0.02
- Priapism · score 0.02
- Red cell distribution width · score 0.02
- Ehlers-Danlos syndrome · score 0.02
- burning mouth syndrome · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99935-F1 | alphafold | PREDICTED | 52.89 | — |
Amino-acid sequence (248 residues)
MKLTFFLGLL ALISCFTPSE SQRFSRRPYL PGQLPPPPLY RPRWVPPSPP PPYDSRLNSP LSLPFVPGRV PPSSFSRFSQ AVILSQLFPL ESIRQPRLFP GYPNLHFPLR PYYVGPIRIL KPPFPPIPFF LAIYLPISNP EPQINITTAD TTITTNPPTT ATATTSTSTK PTMTISSSTV PISSTPEPAT SISAATPAAS TENTTQILAN RPHTVLLNAT VQVTTSNQTI LSSPAFKSFW QKLFAIFG
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