About Retinoic acid receptor responder protein 2
Retinoic acid receptor responder protein 2 (RARRES2) is a protein
from Homo sapiens identified by UniProt accession
Q99969, 163 residues long.
MolForge cross-references it against 0 known binders and
416 disease associations.
Target properties
| Protein name | Retinoic acid receptor responder protein 2 |
|---|
| UniProt accession | Q99969 |
|---|
| Gene | RARRES2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 163 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (416)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- chemerin measurement · score 0.22
- protein measurement · score 0.17
- self reported educational attainment · score 0.16
- platelet count · score 0.14
- appendicular lean mass · score 0.13
- retinoic acid receptor responder protein 2 measurement · score 0.12
- neoplasm · score 0.12
- gestational diabetes · score 0.11
- polycystic ovary syndrome · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99969-F1 | alphafold | PREDICTED | 86.32 | — |
Amino-acid sequence (163 residues)
MRRLLIPLAL WLGAVGVGVA ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFSKAL PRS
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