About Osteomodulin
Osteomodulin (OMD) is a protein
from Homo sapiens identified by UniProt accession
Q99983, 421 residues long.
MolForge cross-references it against 0 known binders and
126 disease associations.
Target properties
| Protein name | Osteomodulin |
|---|
| UniProt accession | Q99983 |
|---|
| Gene | OMD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 421 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (126)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.31
- lung adenocarcinoma · score 0.30
- breast carcinoma · score 0.19
- esophageal squamous cell carcinoma · score 0.19
- pancreatic ductal adenocarcinoma · score 0.19
- gastric carcinoma · score 0.18
- esophageal adenocarcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q99983-F1 | alphafold | PREDICTED | 82.26 | — |
Amino-acid sequence (421 residues)
MGFLSPIYVI FFFFGVKVHC QYETYQWDED YDQEPDDDYQ TGFPFRQNVD YGVPFHQYTL GCVSECFCPT NFPSSMYCDN RKLKTIPNIP MHIQQLYLQF NEIEAVTANS FINATHLKEI NLSHNKIKSQ KIDYGVFAKL PNLLQLHLEH NNLEEFPFPL PKSLERLLLG YNEISKLQTN AMDGLVNLTM LDLCYNYLHD SLLKDKIFAK MEKLMQLNLC SNRLESMPPG LPSSLMYLSL ENNSISSIPE KYFDKLPKLH TLRMSHNKLQ DIPYNIFNLP NIVELSVGHN KLKQAFYIPR NLEHLYLQNN EIEKMNLTVM CPSIDPLHYH HLTYIRVDQN KLKEPISSYI FFCFPHIHTI YYGEQRSTNG QTIQLKTQVF RRFPDDDDES EDHDDPDNAH ESPEQEGAEG HFDLHYYENQ E
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