About B9 domain-containing protein 2
B9 domain-containing protein 2 (B9D2) is a protein
from Homo sapiens identified by UniProt accession
Q9BPU9, 175 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | B9 domain-containing protein 2 |
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| UniProt accession | Q9BPU9 |
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| Gene | B9D2 |
|---|
| Organism | Homo sapiens |
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| Length | 175 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- Joubert syndrome · score 0.74
- Meckel syndrome · score 0.73
- Joubert syndrome and related disorders · score 0.46
- pulse pressure measurement · score 0.29
- cystatin C measurement · score 0.21
- ciliopathy · score 0.19
- colorectal cancer · score 0.18
- coronary artery disease · score 0.17
- blood protein measurement · score 0.14
- Antithrombotic agent use measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BPU9-F1 | alphafold | PREDICTED | 89.62 | — |
Amino-acid sequence (175 residues)
MAEVHVIGQI IGASGFSESS LFCKWGIHTG AAWKLLSGVR EGQTQVDTPQ IGDMAYWSHP IDLHFATKGL QGWPRLHFQV WSQDSFGRCQ LAGYGFCHVP SSPGTHQLAC PTWRPLGSWR EQLARAFVGG GPQLLHGDTI YSGADRYRLH TAAGGTVHLE IGLLLRNFDR YGVEC
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