About Ras-like protein family member 11B
Ras-like protein family member 11B (RASL11B) is a protein
from Homo sapiens identified by UniProt accession
Q9BPW5, 248 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Ras-like protein family member 11B |
|---|
| UniProt accession | Q9BPW5 |
|---|
| Gene | RASL11B |
|---|
| Organism | Homo sapiens |
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| Length | 248 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.47
- neuroimaging measurement · score 0.44
- brain measurement · score 0.41
- cortical thickness · score 0.39
- neurodegenerative disease · score 0.23
- FEV/FVC ratio · score 0.15
- cardiovascular disease · score 0.12
- calcium measurement · score 0.09
- metastasis measurement · score 0.08
- disease progression measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BPW5-F1 | alphafold | PREDICTED | 78.96 | — |
Amino-acid sequence (248 residues)
MRLIQNMCTI AEYPAPGNAA ASDCCVGAAG RRLVKIAVVG ASGVGKTALV VRFLTKRFIG DYERNAGNLY TRQVQIEGET LALQVQDTPG IQVHENSLSC SEQLNRCIRW ADAVVIVFSI TDYKSYELIS QLHQHVQQLH LGTRLPVVVV ANKADLLHIK QVDPQLGLQL ASMLGCSFYE VSVSENYNDV YSAFHVLCKE VSHKQQPSST PEKRRTSLIP RPKSPNMQDL KRRFKQALSA KVRTVTSV
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