UPF0415 protein C7orf25 (C7orf25)

About UPF0415 protein C7orf25

UPF0415 protein C7orf25 (C7orf25) is a protein from Homo sapiens identified by UniProt accession Q9BPX7, 421 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	UPF0415 protein C7orf25
UniProt accession	Q9BPX7
Gene	C7orf25
Organism	Homo sapiens
Length	421 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
BMI-adjusted waist-hip ratio · score 0.24
body height · score 0.23
heel bone mineral density · score 0.23
BMI-adjusted waist circumference · score 0.22
cortical surface area measurement · score 0.22
neuroimaging measurement · score 0.21
body fat percentage · score 0.21
protein measurement · score 0.19
bone quantitative ultrasound measurement · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BPX7-F1	alphafold	PREDICTED	89.65	—

Amino-acid sequence (421 residues)

MSAHSMLCER IAIAKELIKR AESLSRSRKG GIEGGAKLCS KLKAELKFLQ KVEAGKVAIK ESHLQSTNLT HLRAIVESAE NLEEVVSVLH VFGYTDTLGE KQTLVVDVVA NGGHTWVKAI GRKAEALHNI WLGRGQYGDK SIIEQAEDFL QASHQQPVQY SNPHIIFAFY NSVSSPMAEK LKEMGISVRG DIVAVNALLD HPEELQPSES ESDDEGPELL QVTRVDRENI LASVAFPTEI KVDVCKRVNL DITTLITYVS ALSYGGCHFI FKEKVLTEQA EQERKEQVLP QLEAFMKDKE LFACESAVKD FQSILDTLGG PGERERATVL IKRINVVPDQ PSERALRLVA SSKINSRSLT IFGTGDTLKA ITMTANSGFV RAANNQGVKF SVFIHQPRAL TESKEALATP LPKDYTTDSE H

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards