About Protein FAM118B
Protein FAM118B (FAM118B) is a protein
from Homo sapiens identified by UniProt accession
Q9BPY3, 351 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Protein FAM118B |
|---|
| UniProt accession | Q9BPY3 |
|---|
| Gene | FAM118B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 351 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- alkaline phosphatase measurement · score 0.22
- eosinophil count · score 0.17
- body height · score 0.17
- forced expiratory volume · score 0.17
- neutrophil count · score 0.17
- FEV/FVC ratio · score 0.17
- body weight · score 0.16
- leukocyte count · score 0.15
- blood protein measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BPY3-F1 | alphafold | PREDICTED | 83.86 | — |
Amino-acid sequence (351 residues)
MASTGSQASD IDEIFGFFND GEPPTKKPRK LLPSLKTKKP RELVLVIGTG ISAAVAPQVP ALKSWKGLIQ ALLDAAIDFD LLEDEESKKF QKCLHEDKNL VHVAHDLIQK LSPRTSNVRS TFFKDCLYEV FDDLESKMED SGKQLLQSVL HLMENGALVL TTNFDNLLEL YAADQGKQLE SLDLTDEKKV LEWAQEKRKL SVLHIHGVYT NPSGIVLHPA GYQNVLRNTE VMREIQKLYE NKSFLFLGCG WTVDDTTFQA LFLEAVKHKS DLEHFMLVRR GDVDEFKKLR ENMLDKGIKV ISYGDDYADL PEYFKRLTCE ISTRGTSAGM VREGQLNGSS AAHSEIRGCS T
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