Resistin-like beta (RETNLB)

About Resistin-like beta

Resistin-like beta (RETNLB) is a protein from Homo sapiens identified by UniProt accession Q9BQ08, 111 residues long. MolForge cross-references it against 0 known binders and 251 disease associations.

Target properties

Protein name	Resistin-like beta
UniProt accession	Q9BQ08
Gene	RETNLB
Organism	Homo sapiens
Length	111 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (251)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.26
autoimmune disease · score 0.20
thyroid disease · score 0.19
Thyroid preparation use measurement · score 0.11
infection · score 0.09
infect · score 0.09
chronic obstructive pulmonary disease · score 0.08
MODY · score 0.08
non-alcoholic steatohepatitis · score 0.08
oral squamous cell carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQ08-F1	alphafold	PREDICTED	85.61	—

Amino-acid sequence (111 residues)

MGPSSCLLLI LIPLLQLINP GSTQCSLDSV MDKKIKDVLN SLEYSPSPIS KKLSCASVKS QGRPSSCPAG MAVTGCACGY GCGSWDVQLE TTCHCQCSVV DWTTARCCHL T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards