BTB/POZ domain-containing protein KCTD14 (KCTD14)

About BTB/POZ domain-containing protein KCTD14

BTB/POZ domain-containing protein KCTD14 (KCTD14) is a protein from Homo sapiens identified by UniProt accession Q9BQ13, 255 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	BTB/POZ domain-containing protein KCTD14
UniProt accession	Q9BQ13
Gene	KCTD14
Organism	Homo sapiens
Length	255 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.04
Barrett's esophagus · score 0.03
triple-negative breast cancer · score 0.03
breast carcinoma · score 0.02
body height · score 0.02
diastolic blood pressure · score 0.02
Colon Sessile Serrated Adenoma/Polyp · score 0.01
melanoma · score 0.01
systemic lupus erythematosus · score 0.01
sessile serrated polyp · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQ13-F1	alphafold	PREDICTED	85.90	—

Amino-acid sequence (255 residues)

MWQGCAVERP VGRMTSQTPL PQSPRPRRPT MSTVVELNVG GEFHTTTLGT LRKFPGSKLA EMFSSLAKAS TDAEGRFFID RPSTYFRPIL DYLRTGQVPT QHIPEVYREA QFYEIKPLVK LLEDMPQIFG EQVSRKQFLL QVPGYSENLE LMVRLARAEA ITARKSSVLV CLVETEEQDA YYSEVLCFLQ DKKMFKSVVK FGPWKAVLDN SDLMHCLEMD IKAQGYKVFS KFYLTYPTKR NEFHFNIYSF TFTWW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards