About SOSS complex subunit B1
SOSS complex subunit B1 (NABP2) is a protein
from Homo sapiens identified by UniProt accession
Q9BQ15, 211 residues long.
MolForge cross-references it against 0 known binders and
295 disease associations.
Target properties
| Protein name | SOSS complex subunit B1 |
| UniProt accession | Q9BQ15 |
| Gene | NABP2 |
| Organism | Homo sapiens |
| Length | 211 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (295)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.08
- cancer · score 0.07
- cleidocranial dysplasia 1 · score 0.06
- Ear-patella-short stature syndrome · score 0.06
- atelosteogenesis type II · score 0.05
- atelosteogenesis type I · score 0.05
- Achondrogenesis type 1A · score 0.05
- Inguinal hernia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9BQ15-F1 | alphafold | PREDICTED | 76.82 | — |
Amino-acid sequence (211 residues)
MTTETFVKDI KPGLKNLNLI FIVLETGRVT KTKDGHEVRT CKVADKTGSI NISVWDDVGN LIQPGDIIRL TKGYASVFKG CLTLYTGRGG DLQKIGEFCM VYSEVPNFSE PNPEYSTQQA PNKAVQNDSN PSASQPTTGP SAASPASENQ NGNGLSAPPG PGGGPHPPHT PSHPPSTRIT RSQPNHTPAG PPGPSSNPVS NGKETRRSSK R
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