Testican-3 (SPOCK3)

About Testican-3

Testican-3 (SPOCK3) is a protein from Homo sapiens identified by UniProt accession Q9BQ16, 436 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Testican-3
UniProt accession	Q9BQ16
Gene	SPOCK3
Organism	Homo sapiens
Length	436 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.41
response to vaccine · score 0.27
cytokine measurement · score 0.27
inflammatory bowel disease · score 0.25
gut microbiome measurement · score 0.25
breast adenocarcinoma · score 0.22
neuritic plaque measurement · score 0.20
lung adenocarcinoma · score 0.17
cutaneous melanoma · score 0.15
adolescent idiopathic scoliosis · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQ16-F1	alphafold	PREDICTED	66.57	—

Amino-acid sequence (436 residues)

MLKVSAVLCV CAAAWCSQSL AAAAAVAAAG GRSDGGNFLD DKQWLTTISQ YDKEVGQWNK FRDEVEDDYF RTWSPGKPFD QALDPAKDPC LKMKCSRHKV CIAQDSQTAV CISHRRLTHR MKEAGVDHRQ WRGPILSTCK QCPVVYPSPV CGSDGHTYSF QCKLEYQACV LGKQISVKCE GHCPCPSDKP TSTSRNVKRA CSDLEFREVA NRLRDWFKAL HESGSQNKKT KTLLRPERSR FDTSILPICK DSLGWMFNRL DTNYDLLLDQ SELRSIYLDK NEQCTKAFFN SCDTYKDSLI SNNEWCYCFQ RQQDPPCQTE LSNIQKRQGV KKLLGQYIPL CDEDGYYKPT QCHGSVGQCW CVDRYGNEVM GSRINGVADC AIDFEISGDF ASGDFHEWTD DEDDEDDIMN DEDEIEDDDE DEGDDDDGGD DHDVYI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards