Large ribosomal subunit protein bL34m (MRPL34)

About Large ribosomal subunit protein bL34m

Large ribosomal subunit protein bL34m (MRPL34) is a protein from Homo sapiens identified by UniProt accession Q9BQ48, 92 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Large ribosomal subunit protein bL34m
UniProt accession	Q9BQ48
Gene	MRPL34
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
Alzheimer disease · score 0.32
Parkinson disease · score 0.32
multiple sclerosis · score 0.32
lysosomal storage disease · score 0.32
genetic disorder · score 0.12
mitochondrial DNA measurement · score 0.10
breast carcinoma · score 0.09
estrogen-receptor negative breast cancer · score 0.09
ovarian carcinoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQ48-F1	alphafold	PREDICTED	79.61	—

Amino-acid sequence (92 residues)

MAVLAGSLLG PTSRSAALLG GRWLQPRAWL GFPDAWGLPT PQQARGKARG NEYQPSNIKR KNKHGWVRRL STPAGVQVIL RRMLKGRKSL SH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards