About Programmed cell death 1 ligand 2
Programmed cell death 1 ligand 2 (PDCD1LG2) is a protein
from Homo sapiens identified by UniProt accession
Q9BQ51, 273 residues long.
MolForge cross-references it against 0 known binders and
540 disease associations.
Target properties
| Protein name | Programmed cell death 1 ligand 2 |
|---|
| UniProt accession | Q9BQ51 |
|---|
| Gene | PDCD1LG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 273 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (540)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.48
- melanoma · score 0.43
- gastrointestinal stromal tumor · score 0.37
- prostate adenocarcinoma · score 0.37
- lymphoid neoplasm · score 0.37
- kidney neoplasm · score 0.37
- bile duct carcinoma · score 0.37
- Hepatobiliary Neoplasm · score 0.37
- breast ductal adenocarcinoma · score 0.37
- HER2 Positive Breast Carcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BQ51-F1 | alphafold | PREDICTED | 86.35 | — |
Amino-acid sequence (273 residues)
MIFLLLMLSL ELQLHQIAAL FTVTVPKELY IIEHGSNVTL ECNFDTGSHV NLGAITASLQ KVENDTSPHR ERATLLEEQL PLGKASFHIP QVQVRDEGQY QCIIIYGVAW DYKYLTLKVK ASYRKINTHI LKVPETDEVE LTCQATGYPL AEVSWPNVSV PANTSHSRTP EGLYQVTSVL RLKPPPGRNF SCVFWNTHVR ELTLASIDLQ SQMEPRTHPT WLLHIFIPFC IIAFIFIATV IALRKQLCQK LYSSKDTTKR PVTTTKREVN SAI
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