About Keratin-associated protein 4-12
Keratin-associated protein 4-12 (KRTAP4-12) is a protein
from Homo sapiens identified by UniProt accession
Q9BQ66, 201 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Keratin-associated protein 4-12 |
|---|
| UniProt accession | Q9BQ66 |
|---|
| Gene | KRTAP4-12 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- body mass index · score 0.07
- lean body mass · score 0.06
- fat body mass · score 0.06
- colorectal adenocarcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.04
- whole body water mass · score 0.04
- waist circumference · score 0.04
- base metabolic rate measurement · score 0.04
- body weight · score 0.03
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BQ66-F1 | alphafold | PREDICTED | 35.57 | — |
Amino-acid sequence (201 residues)
MVNSCCGSVC SDQGCGLENC CRPSCCQTTC CRTTCCRPSC CVSSCCRPQC CQSVCCQPTC CRPSCCQTTC CRTTCCRPSC CVSSCCRPQC CQSVCCQPTC CRPSCCQTTC CRTTCCRPSC CVSSCCRPQC CQSVCCQPTC CRPSCCISSS CCPSCCESSC CRPCCCLRPV CGRVSCHTTC YRPTCVISTC PRPLCCASSC C
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