About Protein CMSS1
Protein CMSS1 (CMSS1) is a protein
from Homo sapiens identified by UniProt accession
Q9BQ75, 279 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | Protein CMSS1 |
|---|
| UniProt accession | Q9BQ75 |
|---|
| Gene | CMSS1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 279 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.39
- appendicular lean mass · score 0.32
- BMI-adjusted waist circumference · score 0.32
- BMI-adjusted hip circumference · score 0.30
- breast carcinoma · score 0.29
- body fat percentage · score 0.29
- heel bone mineral density · score 0.27
- BMI-adjusted waist-hip ratio · score 0.27
- waist-hip ratio · score 0.27
- pulse pressure measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BQ75-F1 | alphafold | PREDICTED | 79.90 | — |
Amino-acid sequence (279 residues)
MADDLGDEWW ENQPTGAGSS PEASDGEGEG DTEVMQQETV PVPVPSEKTK QPKECFLIQP KERKENTTKT RKRRKKKITD VLAKSEPKPG LPEDLQKLMK DYYSSRRLVI ELEELNLPDS CFLKANDLTH SLSSYLKEIC PKWVKLRKNH SEKKSVLMLI ICSSAVRALE LIRSMTAFRG DGKVIKLFAK HIKVQAQVKL LEKRVVHLGV GTPGRIKELV KQGGLNLSPL KFLVFDWNWR DQKLRRMMDI PEIRKEVFEL LEMGVLSLCK SESLKLGLF
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