Large ribosomal subunit protein mL63 (MRPL57)

About Large ribosomal subunit protein mL63

Large ribosomal subunit protein mL63 (MRPL57) is a protein from Homo sapiens identified by UniProt accession Q9BQC6, 102 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL63
UniProt accession	Q9BQC6
Gene	MRPL57
Organism	Homo sapiens
Length	102 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.15
chronic bronchitis · score 0.04
systolic blood pressure · score 0.03
BMI-adjusted hip circumference · score 0.03
forced expiratory volume · score 0.03
glucuronate measurement · score 0.03
adolescent idiopathic scoliosis · score 0.02
pancreatic ductal adenocarcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQC6-F1	alphafold	PREDICTED	92.38	—

Amino-acid sequence (102 residues)

MFLTALLWRG RIPGRQWIGK HRRPRFVSLR AKQNMIRRLE IEAENHYWLS MPYMTREQER GHAAVRRREA FEAIKAAATS KFPPHRFIAD QLDHLNVTKK WS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards