KxDL motif-containing protein 1 (KXD1)

About KxDL motif-containing protein 1

KxDL motif-containing protein 1 (KXD1) is a protein from Homo sapiens identified by UniProt accession Q9BQD3, 176 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	KxDL motif-containing protein 1
UniProt accession	Q9BQD3
Gene	KXD1
Organism	Homo sapiens
Length	176 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
multiple sclerosis · score 0.18
Alzheimer disease · score 0.18
Parkinson disease · score 0.18
lysosomal storage disease · score 0.18
retinitis pigmentosa · score 0.07
choroidal dystrophy, central areolar, 1 · score 0.05
Nephronophthisis · score 0.05
nephronophthisis · score 0.05
choroideremia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQD3-F1	alphafold	PREDICTED	75.71	—

Amino-acid sequence (176 residues)

MDLPDSASRV FCGRILSMVN TDDVNAIILA QKNMLDRFEK TNEMLLNFNN LSSARLQQMS ERFLHHTRTL VEMKRDLDSI FRRIRTLKGK LARQHPEAFS HIPEASFLEE EDEDPIPPST TTTIATSEQS TGSCDTSPDT VSPSLSPGFE DLSHVQPGSP AINGRSQTDD EEMTGE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards