About Adenine nucleotide translocase lysine N-methyltransferase
Adenine nucleotide translocase lysine N-methyltransferase (ANTKMT) is a protein
from Homo sapiens identified by UniProt accession
Q9BQD7, 235 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Adenine nucleotide translocase lysine N-methyltransferase |
|---|
| UniProt accession | Q9BQD7 |
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| Gene | ANTKMT |
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| Organism | Homo sapiens |
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| Length | 235 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (18)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.11
- bone fracture · score 0.04
- attention deficit hyperactivity disorder · score 0.03
- Testicular regression syndrome · score 0.03
- 46,XX ovotesticular disorder of sex development · score 0.03
- body height · score 0.03
- mean corpuscular hemoglobin · score 0.03
- appendicular lean mass · score 0.03
- mean corpuscular volume · score 0.03
- BMI-adjusted hip circumference · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BQD7-F1 | alphafold | PREDICTED | 81.52 | — |
Amino-acid sequence (235 residues)
MEQDDPVEAL TELRERRLGA LELLQAAAGS GLAAYAVWAL LLQPGFRRVP LRLQVPYVGA SARQVEHVLS LLRGRPGKTV DLGSGDGRIV LAAHRCGLRP AVGYELNPWL VALARLHAWR AGCAGSVCYR RKDLWKVSLR DCRNVSVFLA PSVLPLLEDK LRTELPAGAR VVSGRFPLPT WQPVTAVGEG LDRVWAYDVP EGGQAGEAAS SRIPIQAAPG PSSAPIPGGL ISQAS
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