Golgi reassembly-stacking protein 1 (GORASP1)

About Golgi reassembly-stacking protein 1

Golgi reassembly-stacking protein 1 (GORASP1) is a protein from Homo sapiens identified by UniProt accession Q9BQQ3, 440 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Golgi reassembly-stacking protein 1
UniProt accession	Q9BQQ3
Gene	GORASP1
Organism	Homo sapiens
Length	440 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

Follicular Cyst · score 0.12
self reported educational attainment · score 0.10
cognitive decline measurement · score 0.08
brain-derived neurotrophic factor measurement · score 0.04
cytomegalovirus infection · score 0.04
histidinemia · score 0.04
mitochondrial DNA measurement · score 0.04
serum gamma-glutamyl transferase measurement · score 0.03
platelet component distribution width · score 0.03
sex hormone-binding globulin measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQQ3-F1	alphafold	PREDICTED	63.14	—

Amino-acid sequence (440 residues)

MGLGVSAEQP AGGAEGFHLH GVQENSPAQQ AGLEPYFDFI ITIGHSRLNK ENDTLKALLK ANVEKPVKLE VFNMKTMRVR EVEVVPSNMW GGQGLLGASV RFCSFRRASE QVWHVLDVEP SSPAALAGLR PYTDYVVGSD QILQESEDFF TLIESHEGKP LKLMVYNSKS DSCREVTVTP NAAWGGEGSL GCGIGYGYLH RIPTQPPSYH KKPPGTPPPS ALPLGAPPPD ALPPGPTPED SPSLETGSRQ SDYMEALLQA PGSSMEDPLP GPGSPSHSAP DPDGLPHFME TPLQPPPPVQ RVMDPGFLDV SGISLLDNSN ASVWPSLPSS TELTTTAVST SGPEDICSSS SSHERGGEAT WSGSEFEVSF LDSPGAQAQA DHLPQLTLPD SLTSAASPED GLSAELLEAQ AEEEPASTEG LDTGTEAEGL DSQAQISTTE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards