Thioredoxin domain-containing protein 17 (TXNDC17)

About Thioredoxin domain-containing protein 17

Thioredoxin domain-containing protein 17 (TXNDC17) is a protein from Homo sapiens identified by UniProt accession Q9BRA2, 123 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

Target properties

Protein name	Thioredoxin domain-containing protein 17
UniProt accession	Q9BRA2
Gene	TXNDC17
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (29)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.34
systolic blood pressure · score 0.21
body height · score 0.19
pulse pressure measurement · score 0.17
diastolic blood pressure · score 0.16
BMI-adjusted waist circumference · score 0.15
testosterone measurement · score 0.13
forced expiratory volume · score 0.11
heel bone mineral density · score 0.04
visual perception measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BRA2-F1	alphafold	PREDICTED	95.81	—

Amino-acid sequence (123 residues)

MARYEEVSVS GFEEFHRAVE QHNGKTIFAY FTGSKDAGGK SWCPDCVQAE PVVREGLKHI SEGCVFIYCQ VGEKPYWKDP NNDFRKNLKV TAVPTLLKYG TPQKLVESEC LQANLVEMLF SED

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards