Zinc finger protein 649 (ZNF649)

About Zinc finger protein 649

Zinc finger protein 649 (ZNF649) is a protein from Homo sapiens identified by UniProt accession Q9BS31, 505 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Zinc finger protein 649
UniProt accession	Q9BS31
Gene	ZNF649
Organism	Homo sapiens
Length	505 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

high density lipoprotein cholesterol measurement · score 0.04
apolipoprotein A 1 measurement · score 0.03
cognitive domain measurement · score 0.03
neoplasm · score 0.01
multiple sclerosis · score 0.00
ulcerative colitis · score 0.00
lung adenocarcinoma · score 0.00
inflammatory bowel disease · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BS31-F1	alphafold	PREDICTED	68.49	—

Amino-acid sequence (505 residues)

MTKAQESLTL EDVAVDFTWE EWQFLSPAQK DLYRDVMLEN YSNLVSVGYQ AGKPDALTKL EQGEPLWTLE DEIHSPAHPE IEKADDHLQQ PLQNQKILKR TGQRYEHGRT LKSYLGLTNQ SRRYNRKEPA EFNGDGAFLH DNHEQMPTEI EFPESRKPIS TKSQFLKHQQ THNIEKAHEC TDCGKAFLKK SQLTEHKRIH TGKKPHVCSL CGKAFYKKYR LTEHERAHRG EKPHGCSLCG KAFYKRYRLT EHERAHKGEK PYGCSECGKA FPRKSELTEH QRIHTGIKPH QCSECGRAFS RKSLLVVHQR THTGEKPHTC SECGKGFIQK GNLNIHQRTH TGEKPYGCID CGKAFSQKSC LVAHQRYHTG KTPFVCPECG QPCSQKSGLI RHQKIHSGEK PYKCSDCGKA FLTKTMLIVH HRTHTGERPY GCDECEKAYF YMSCLVKHKR IHSREKRGDS VKVENPSTAS HSLSPSEHVQ GKSPVNMVTV AMVAGQCEFA HILHS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards