About Latexin
Latexin (LXN) is a protein
from Homo sapiens identified by UniProt accession
Q9BS40, 222 residues long.
MolForge cross-references it against 0 known binders and
92 disease associations.
Target properties
| Protein name | Latexin |
|---|
| UniProt accession | Q9BS40 |
|---|
| Gene | LXN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (92)
Diseases linked to this target (Open Targets).
- hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 · score 0.57
- Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 · score 0.57
- combined oxidative phosphorylation deficiency · score 0.34
- diastolic blood pressure · score 0.29
- systolic blood pressure · score 0.20
- genetic disorder · score 0.19
- PR interval · score 0.13
- Developmental regression · score 0.12
- Relative macrocephaly · score 0.12
- Severe muscular hypotonia · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BS40-F1 | alphafold | PREDICTED | 95.96 | — |
Amino-acid sequence (222 residues)
MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYHLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE
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