Protein NipSnap homolog 3B (NIPSNAP3B)

About Protein NipSnap homolog 3B

Protein NipSnap homolog 3B (NIPSNAP3B) is a protein from Homo sapiens identified by UniProt accession Q9BS92, 247 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein name	Protein NipSnap homolog 3B
UniProt accession	Q9BS92
Gene	NIPSNAP3B
Organism	Homo sapiens
Length	247 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (58)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.24
3-hydroxyisobutyrate measurement · score 0.21
Tangier disease · score 0.15
high density lipoprotein cholesterol measurement · score 0.11
low density lipoprotein cholesterol measurement · score 0.10
reticulocyte count · score 0.10
reticulocyte measurement · score 0.09
total cholesterol measurement · score 0.08
apolipoprotein A 1 measurement · score 0.07
C-reactive protein measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BS92-F1	alphafold	PREDICTED	90.97	—

Amino-acid sequence (247 residues)

MLVLRSGLTK ALASRTLAPQ VCSSFATGPR QYDGTFYEFR TYYLKPSNMN AFMENLKKNI HLRTSYSELV GFWSVEFGGR TNKVFHIWKY DNFAHRAEVR KALANCKEWQ EQSIIPNLAR IDKQETEITY LIPWSKLEKP PKEGVYELAV FQMKPGGPAL WGDAFERAIN AHVNLGYTKV VGVFHTEYGE LNRVHVLWWN ESADSRAAGR HKSHEDPRVV AAVRESVNYL VSQQNMLLIP ASFSPLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards