About Nucleolar protein 10
Nucleolar protein 10 (NOL10) is a protein
from Homo sapiens identified by UniProt accession
Q9BSC4, 688 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Nucleolar protein 10 |
|---|
| UniProt accession | Q9BSC4 |
|---|
| Gene | NOL10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 688 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.41
- prostate carcinoma · score 0.33
- alcohol drinking · score 0.09
- hepatocellular carcinoma · score 0.03
- glycogen storage disease VI · score 0.01
- laryngotracheoesophageal cleft · score 0.01
- cancer · score 0.01
- triple-negative breast cancer · score 0.01
- neoplasm · score 0.01
- breast cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BSC4-F1 | alphafold | PREDICTED | 77.63 | — |
Amino-acid sequence (688 residues)
MQVSSLNEVK IYSLSCGKSL PEWLSDRKKR ALQKKDVDVR RRIELIQDFE MPTVCTTIKV SKDGQYILAT GTYKPRVRCY DTYQLSLKFE RCLDSEVVTF EILSDDYSKI VFLHNDRYIE FHSQSGFYYK TRIPKFGRDF SYHYPSCDLY FVGASSEVYR LNLEQGRYLN PLQTDAAENN VCDINSVHGL FATGTIEGRV ECWDPRTRNR VGLLDCALNS VTADSEINSL PTISALKFNG ALTMAVGTTT GQVLLYDLRS DKPLLVKDHQ YGLPIKSVHF QDSLDLILSA DSRIVKMWNK NSGKIFTSLE PEHDLNDVCL YPNSGMLLTA NETPKMGIYY IPVLGPAPRW CSFLDNLTEE LEENPESTVY DDYKFVTKKD LENLGLTHLI GSPFLRAYMH GFFMDIRLYH KVKLMVNPFA YEEYRKDKIR QKIEETRAQR VQLKKLPKVN KELALKLIEE EEEKQKSTWK KKVKSLPNIL TDDRFKVMFE NPDFQVDEES EEFRLLNPLV SKISEKRKKK LRLLEQQELR EKEEEEEPEG KPSDAESSES SDDEKAWVEE VRKQRRLLQQ EEKVKRQERL KEDQQTVLKP QFYEIKAGEE FRSFKDSATK QKLMNKTLED RLKIEAKNGT LSVSDTTVGS KQLTFTLKRS EQQKKQQEAE KLHRQERKRL RRSAGHLKSR HKRGRSFH
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