About Retbindin
Retbindin (RTBDN) is a protein
from Homo sapiens identified by UniProt accession
Q9BSG5, 229 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Retbindin |
|---|
| UniProt accession | Q9BSG5 |
|---|
| Gene | RTBDN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 229 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- mean corpuscular hemoglobin concentration · score 0.25
- mean corpuscular volume · score 0.15
- Red cell distribution width · score 0.08
- heel bone mineral density · score 0.08
- reticulocyte measurement · score 0.06
- mathematical ability · score 0.05
- HbA1c measurement · score 0.05
- Familial exudative vitreoretinopathy · score 0.05
- body mass index · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BSG5-F1 | alphafold | PREDICTED | 65.63 | — |
Amino-acid sequence (229 residues)
MDCRVHMRPI GLTWVLQLTL AWILLEACGG SRPLQARSQQ HHGLAADLGK GKLHLAGPCC PSEMDTTETS GPGNHPERCG VPSPECESFL EHLQRALRSR FRLRLLGVRQ AQPLCEELCQ AWFANCEDDI TCGPTWLPLS EKRGCEPSCL TYGQTFADGT DLCRSALGHA LPVAAPGARH CFNISISAVP RPRPGRRGRE APSRRSRSPR TSILDAAGSG SGSGSGSGP
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