About Rhotekin
Rhotekin (RTKN) is a protein
from Homo sapiens identified by UniProt accession
Q9BST9, 563 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Rhotekin |
|---|
| UniProt accession | Q9BST9 |
|---|
| Gene | RTKN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 563 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- gonorrhea · score 0.08
- Stress urinary incontinence · score 0.06
- platelet count · score 0.03
- neoplasm · score 0.03
- appendicular lean mass · score 0.02
- hepatocellular carcinoma · score 0.02
- glioblastoma · score 0.02
- urinary bladder carcinoma · score 0.02
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BST9-F1 | alphafold | PREDICTED | 71.98 | — |
Amino-acid sequence (563 residues)
MFSRNHRSRV TVARGSALEM EFKRGRFRLS LFSDLPEDTE LQRKLDHEIR MREGACKLLA ACSQREQALE ATKSLLVCNS RILSYMGELQ RRKEAQVLGK TSRRPSDSGP PAERSPCRGR VCISDLRIPL MWKDTEYFKN KGDLHRWAVF LLLQLGEHIQ DTEMILVDRT LTDISFQSNV LFAEAGPDFE LRLELYGACV EEEGALTGGP KRLATKLSSS LGRSSGRRVR ASLDSAGGSG SSPILLPTPV VGGPRYHLLA HTTLTLAAVQ DGFRTHDLTL ASHEENPAWL PLYGSVCCRL AAQPLCMTQP TASGTLRVQQ AGEMQNWAQV HGVLKGTNLF CYRQPEDADT GEEPLLTIAV NKETRVRAGE LDQALGRPFT LSISNQYGDD EVTHTLQTES REALQSWMEA LWQLFFDMSQ WKQCCDEIMK IETPAPRKPP QALAKQGSLY HEMAIEPLDD IAAVTDILTQ REGARLETPP PWLAMFTDQP ALPNPCSPAS VAPAPDWTHP LPWGRPRTFS LDAVPPDHSP RARSVAPLPP QRSPRTRGLC SKGQPRTWLQ SPV
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