HAUS augmin-like complex subunit 8 (HAUS8)

About HAUS augmin-like complex subunit 8

HAUS augmin-like complex subunit 8 (HAUS8) is a protein from Homo sapiens identified by UniProt accession Q9BT25, 410 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	HAUS augmin-like complex subunit 8
UniProt accession	Q9BT25
Gene	HAUS8
Organism	Homo sapiens
Length	410 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.37
diastolic blood pressure · score 0.37
mean platelet volume · score 0.36
platelet count · score 0.32
BMI-adjusted waist-hip ratio · score 0.31
hypertension · score 0.28
asthma · score 0.27
appendicular lean mass · score 0.24
reticulocyte count · score 0.24
ovarian cancer · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BT25-F1	alphafold	PREDICTED	68.48	—

Amino-acid sequence (410 residues)

MADSSGRGAG KPATGPTNSS SAKKKDKRVQ GGRVIESRYL QYEKKTTQKA PAGDGSQTRG KMSEGGRKSS LLQKSKADSS GVGKGDLQST LLEGHGTAPP DLDLSAINDK SIVKKTPQLA KTISKKPEST SFSAPRKKSP DLSEAMEMME SQTLLLTLLS VKMENNLAEF ERRAEKNLLI MCKEKEKLQK KAHELKRRLL LSQRKRELAD VLDAQIEMLS PFEAVATRFK EQYRTFATAL DTTRHELPVR SIHLEGDGQQ LLDALQHELV TTQRLLGELD VGDSEENVQV LDLLSELKDV TAKKDLELRR SFAQVLELSA EASKEAALAN QEVWEETQGM APPSRWYFNQ DSACRESGGA PKNTPLSEDD NPGASSAPAQ ATFISPSEDF SSSSQAEVPP SLSRSGRDLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards