About THAP domain-containing protein 7
THAP domain-containing protein 7 (THAP7) is a protein
from Homo sapiens identified by UniProt accession
Q9BT49, 309 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | THAP domain-containing protein 7 |
|---|
| UniProt accession | Q9BT49 |
|---|
| Gene | THAP7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 309 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- pain · score 0.10
- lung adenocarcinoma · score 0.07
- Inguinal hernia · score 0.04
- neoplasm · score 0.03
- metabolite measurement · score 0.02
- gonorrhea · score 0.01
- infect · score 0.01
- infection · score 0.01
- chronic kidney disease · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BT49-F1 | alphafold | PREDICTED | 69.66 | — |
Amino-acid sequence (309 residues)
MPRHCSAAGC CTRDTRETRN RGISFHRLPK KDNPRRGLWL ANCQRLDPSG QGLWDPASEY IYFCSKHFEE DCFELVGISG YHRLKEGAVP TIFESFSKLR RTTKTKGHSY PPGPAEVSRL RRCRKRCSEG RGPTTPFSPP PPADVTCFPV EEASAPATLP ASPAGRLEPG LSSPFSDLLG PLGAQADEAG CSAQPSPERQ PSPLEPRPVS PSAYMLRLPP PAGAYIQNEH SYQVGSALLW KRRAEAALDA LDKAQRQLQA CKRREQRLRL RLTKLQQERA REKRAQADAR QTLKEHVQDF AMQLSSSMA
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