About NEDD4 family-interacting protein 1
NEDD4 family-interacting protein 1 (NDFIP1) is a protein
from Homo sapiens identified by UniProt accession
Q9BT67, 221 residues long.
MolForge cross-references it against 0 known binders and
217 disease associations.
Target properties
| Protein name | NEDD4 family-interacting protein 1 |
|---|
| UniProt accession | Q9BT67 |
|---|
| Gene | NDFIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (217)
Diseases linked to this target (Open Targets).
- platelet count · score 0.35
- neutrophil count · score 0.34
- eosinophil count · score 0.34
- leukocyte count · score 0.33
- asthma · score 0.32
- mean corpuscular hemoglobin concentration · score 0.32
- mean corpuscular volume · score 0.32
- Crohn's disease · score 0.30
- inflammatory bowel disease · score 0.29
- erythrocyte count · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BT67-F1 | alphafold | PREDICTED | 62.57 | — |
Amino-acid sequence (221 residues)
MALALAALAA VEPACGSRYQ QLQNEEESGE PEQAAGDAPP PYSSISAESA AYFDYKDESG FPKPPSYNVA TTLPSYDEAE RTKAEATIPL VPGRDEDFVG RDDFDDADQL RIGNDGIFML TFFMAFLFNW IGFFLSFCLT TSAAGRYGAI SGFGLSLIKW ILIVRFSTYF PGYFDGQYWL WWVFLVLGFL LFLRGFINYA KVRKMPETFS NLPRTRVLFI Y
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