About Uroplakin-3b
Uroplakin-3b (UPK3B) is a protein
from Homo sapiens identified by UniProt accession
Q9BT76, 320 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Uroplakin-3b |
|---|
| UniProt accession | Q9BT76 |
|---|
| Gene | UPK3B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 320 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- CCL24 measurement · score 0.13
- refractive error measurement · score 0.11
- heat shock 27 kDa protein measurement · score 0.06
- osteoarthritis · score 0.05
- COVID-19 · score 0.05
- diet measurement · score 0.05
- Sepsis · score 0.04
- puerperal disorder · score 0.04
- adolescent idiopathic scoliosis · score 0.04
- neoplasm · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BT76-F1 | alphafold | PREDICTED | 52.73 | — |
Amino-acid sequence (320 residues)
MGLPWGQPHL GLQMLLLALN CLRPSLSLGE WGSWMDASSQ TQGAGGPAGV IGPWAPAPLR LGEAAPGTPT PVSVAHLLSP VATELVPYTP QITAWDLEGK VTATTFSLEQ PRCVFDGLAS ASDTVWLVVA FSNASRGFQN PETLADIPAS PQLLTDGHYM TLPLSPDQLP CGDPMAGSGG APVLRVGHDH GCHQQPFCNA PLPGPGPYRE DPRIHRHLAR AAKWQHDRHY LHPLFSGRPP TLGLLGSLYH ALLQPVVAGG GPGAAADRLL HGQALHDPPH PTQRGRHTAG GLQAWPGPPP QPQPLAWPLC MGLGEMGRWE
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