Transcription factor SOX-7 (SOX7)

About Transcription factor SOX-7

Transcription factor SOX-7 (SOX7) is a protein from Homo sapiens identified by UniProt accession Q9BT81, 388 residues long. MolForge cross-references it against 0 known binders and 185 disease associations.

Target properties

Protein name	Transcription factor SOX-7
UniProt accession	Q9BT81
Gene	SOX7
Organism	Homo sapiens
Length	388 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (185)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.34
systolic blood pressure · score 0.31
smoking status measurement · score 0.31
HbA1c measurement · score 0.29
diastolic blood pressure · score 0.28
total blood protein measurement · score 0.27
triglyceride measurement · score 0.26
hypertension · score 0.25
lymphocyte count · score 0.25
high density lipoprotein cholesterol measurement · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BT81-F1	alphafold	PREDICTED	59.95	—

Amino-acid sequence (388 residues)

MASLLGAYPW PEGLECPALD AELSDGQSPP AVPRPPGDKG SESRIRRPMN AFMVWAKDER KRLAVQNPDL HNAELSKMLG KSWKALTLSQ KRPYVDEAER LRLQHMQDYP NYKYRPRRKK QAKRLCKRVD PGFLLSSLSR DQNALPEKRS GSRGALGEKE DRGEYSPGTA LPSLRGCYHE GPAGGGGGGT PSSVDTYPYG LPTPPEMSPL DVLEPEQTFF SSPCQEEHGH PRRIPHLPGH PYSPEYAPSP LHCSHPLGSL ALGQSPGVSM MSPVPGCPPS PAYYSPATYH PLHSNLQAHL GQLSPPPEHP GFDALDQLSQ VELLGDMDRN EFDQYLNTPG HPDSATGAMA LSGHVPVSQV TPTGPTETSL ISVLADATAT YYNSYSVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards