Ubiquitin-related modifier 1 (URM1)

About Ubiquitin-related modifier 1

Ubiquitin-related modifier 1 (URM1) is a protein from Homo sapiens identified by UniProt accession Q9BTM9, 101 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Ubiquitin-related modifier 1
UniProt accession	Q9BTM9
Gene	URM1
Organism	Homo sapiens
Length	101 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
fat body mass · score 0.12
body weights and measures · score 0.09
body fat percentage · score 0.09
hypertriglyceridemia 2 · score 0.06
isolated asymptomatic elevation of creatine phosphokinase · score 0.06
cholesterol-ester transfer protein deficiency · score 0.05
neoplasm · score 0.05
Combined hyperlipidemia · score 0.05
pentosuria · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BTM9-F1	alphafold	PREDICTED	94.05	—

Amino-acid sequence (101 residues)

MAAPLSVEVE FGGGAELLFD GIKKHRVTLP GQEEPWDIRN LLIWIKKNLL KERPELFIQG DSVRPGILVL INDADWELLG ELDYQLQDQD SVLFISTLHG G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards