About Fibronectin type III and SPRY domain-containing protein 1
Fibronectin type III and SPRY domain-containing protein 1 (FSD1) is a protein
from Homo sapiens identified by UniProt accession
Q9BTV5, 496 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Fibronectin type III and SPRY domain-containing protein 1 |
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| UniProt accession | Q9BTV5 |
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| Gene | FSD1 |
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| Organism | Homo sapiens |
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| Length | 496 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- response to bronchodilator · score 0.02
- vital capacity · score 0.02
- vitamin D measurement · score 0.02
- uterine leiomyosarcoma · score 0.01
- Alzheimer disease · score 0.01
- Friedreich ataxia · score 0.00
- viral disease · score 0.00
- neoplasm · score 0.00
- Pick disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BTV5-F1 | alphafold | PREDICTED | 87.53 | — |
Amino-acid sequence (496 residues)
MEEQREALRK IIKTLAVKNE EIQSFIYSLK QMLLNVEANS AKVQEDLEAE FQSLFSLLEE LKEGMLMKIK QDRASRTYEL QNQLAACTRA LESSEELLET ANQTLQAMDS EDFPQAAKQI KDGVTMAPAF RLSLKAKVSD NMSHLMVDFA QERQMLQALK FLPVPSAPVI DLAESLVADN CVTLVWRMPD EDSKIDHYVL EYRRTNFEGP PRLKEDQPWM VIEGIRQTEY TLTGLKFDMK YMNFRVKACN KAVAGEFSEP VTLETPAFMF RLDASTSHQN LRVDDLSVEW DAMGGKVQDI KAREKDGKGR TASPINSPAR GTPSPKRMPS GRGGRDRFTA ESYTVLGDTL IDGGEHYWEV RYEPDSKAFG VGVAYRSLGR FEQLGKTAAS WCLHVNNWLQ VSFTAKHANK VKVLDAPVPD CLGVHCDFHQ GLLSFYNART KQVLHTFKTR FTQPLLPAFT VWCGSFQVTT GLQVPSAVRC LQKRGSATSS SNTSLT
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