About Transmembrane protein 208
Transmembrane protein 208 (TMEM208) is a protein
from Homo sapiens identified by UniProt accession
Q9BTX3, 173 residues long.
MolForge cross-references it against 0 known binders and
16 disease associations.
Target properties
| Protein name | Transmembrane protein 208 |
|---|
| UniProt accession | Q9BTX3 |
|---|
| Gene | TMEM208 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 173 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (16)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.11
- head and neck squamous cell carcinoma · score 0.07
- mean corpuscular hemoglobin concentration · score 0.05
- heel bone mineral density · score 0.04
- neoplasm · score 0.04
- mean corpuscular hemoglobin · score 0.03
- erythrocyte count · score 0.03
- bone quantitative ultrasound measurement · score 0.02
- appendicular lean mass · score 0.02
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BTX3-F1 | alphafold | PREDICTED | 78.13 | — |
Amino-acid sequence (173 residues)
MAPKGKVGTR GKKQIFEENR ETLKFYLRII LGANAIYCLV TLVFFYSSAS FWAWLALGFS LAVYGASYHS MSSMARAAFS EDGALMDGGM DLNMEQGMAE HLKDVILLTA IVQVLSCFSL YVWSFWLLAP GRALYLLWVN VLGPWFTADS GTPAPEHNEK RQRRQERRQM KRL
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