Co-chaperone protein HGH1 homolog (HGH1)

About Co-chaperone protein HGH1 homolog

Co-chaperone protein HGH1 homolog (HGH1) is a protein from Homo sapiens identified by UniProt accession Q9BTY7, 390 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Co-chaperone protein HGH1 homolog
UniProt accession	Q9BTY7
Gene	HGH1
Organism	Homo sapiens
Length	390 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

serum alanine aminotransferase measurement · score 0.14
body height · score 0.04
mean corpuscular volume · score 0.03
type 2 diabetes mellitus · score 0.03
BMI-adjusted waist circumference · score 0.03
cancer · score 0.03
complication · score 0.02
blood protein measurement · score 0.02
serum metabolite measurement · score 0.02
breast cancer · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BTY7-F1	alphafold	PREDICTED	90.88	—

Amino-acid sequence (390 residues)

MGEAGAGAGA SGGPEASPEA EVVKLLPFLA PGARADLQAA AVRHVLALTG CGPGRALLAG QAALLQALME LAPASAPARD AARALVNLAA DPGLHETLLA ADPGLPARLM GRALDPQWPW AEEAAAALAN LSREPAPCAA LMAALAAAEP ADSGLERLVR ALCTPGYNAR APLHYLAPLL SNLSQRPAAR AFLLDPDRCV VQRLLPLTQY PDSSVRRGGV VGTLRNCCFE HRHHEWLLGP EVDILPFLLL PLAGPEDFSE EEMERLPVDL QYLPPDKQRE PDADIRKMLV EAIMLLTATA PGRQQVRDQG AYLILRELHS WEPEPDVRTA CEKLIQVLIG DEPERGMENL LEVQVPEDVE QQLQQLDCRE QEQLERELAP EPWVERATPT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards