Dehydrogenase/reductase SDR family member 4 (DHRS4)

About Dehydrogenase/reductase SDR family member 4

Dehydrogenase/reductase SDR family member 4 (DHRS4) is a protein from Homo sapiens identified by UniProt accession Q9BTZ2, 278 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Dehydrogenase/reductase SDR family member 4
UniProt accession	Q9BTZ2
Gene	DHRS4
Organism	Homo sapiens
Length	278 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BTZ2-F1	alphafold	PREDICTED	91.46	—

Amino-acid sequence (278 residues)

MHKAGLLGLC ARAWNSVRMA SSGMTRRDPL ANKVALVTAS TDGIGFAIAR RLAQDGAHVV VSSRKQQNVD QAVATLQGEG LSVTGTVCHV GKAEDRERLV ATAVKLHGGI DILVSNAAVN PFFGSIMDVT EEVWDKTLDI NVKAPALMTK AVVPEMEKRG GGSVVIVSSI AAFSPSPGFS PYNVSKTALL GLTKTLAIEL APRNIRVNCL APGLIKTSFS RMLWMDKEKE ESMKETLRIR RLGEPEDCAG IVSFLCSEDA SYITGETVVV GGGTPSRL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards