Proline-rich protein 15-like protein (PRR15L)

About Proline-rich protein 15-like protein

Proline-rich protein 15-like protein (PRR15L) is a protein from Homo sapiens identified by UniProt accession Q9BU68, 103 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Proline-rich protein 15-like protein
UniProt accession	Q9BU68
Gene	PRR15L
Organism	Homo sapiens
Length	103 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

type 1 diabetes mellitus · score 0.32
neutrophil count · score 0.14
blood protein measurement · score 0.13
FEV/FVC ratio · score 0.12
erythrocyte count · score 0.09
protein measurement · score 0.08
mean corpuscular hemoglobin · score 0.08
birth weight · score 0.05
high density lipoprotein cholesterol measurement · score 0.05
insomnia measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BU68-F1	alphafold	PREDICTED	63.53	—

Amino-acid sequence (103 residues)

MTTEIGWWKL TFLRKKKSTP KVLYEIPDTY AQTEGDAEPP RPDAGGPNSD FNTRLEKIVD KSTKGKHVKV SNSGRFKEKK KVRATLAENP NLFDDHEEGR SSK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards