Multiple myeloma tumor-associated protein 2 (MMTAG2)

About Multiple myeloma tumor-associated protein 2

Multiple myeloma tumor-associated protein 2 (MMTAG2) is a protein from Homo sapiens identified by UniProt accession Q9BU76, 263 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Multiple myeloma tumor-associated protein 2
UniProt accession	Q9BU76
Gene	MMTAG2
Organism	Homo sapiens
Length	263 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.03
hypertension · score 0.03
cortical surface area measurement · score 0.03
cardiovascular disease · score 0.02
multiple myeloma · score 0.01
Dravet syndrome · score 0.01
hepatocellular carcinoma · score 0.01
Miyoshi myopathy · score 0.01
preeclampsia · score 0.00
plasma cell neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BU76-F1	alphafold	PREDICTED	62.75	—

Amino-acid sequence (263 residues)

MFGSSRGGVR GGQDQFNWED VKTDKQRENY LGNSLMAPVG RWQKGRDLTW YAKGRAPCAG PSREEELAAV REAEREALLA ALGYKNVKKQ PTGLSKEDFA EVCKREGGDP EEKGVDRLLG LGSASGSVGR VAMSREDKEA AKLGLSVFTH HRVESGGPGT SAASARRKPR AEDQTESSCE SHRKSKKEKK KKKKRKHKKE KKKKDKEHRR PAEATSSPTS PERPRHHHHD SDSNSPCCKR RKRGHSGDRR SPSRRWHDRG SEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards