Transmembrane protein 243 (TMEM243)

About Transmembrane protein 243

Transmembrane protein 243 (TMEM243) is a protein from Homo sapiens identified by UniProt accession Q9BU79, 118 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Transmembrane protein 243
UniProt accession	Q9BU79
Gene	TMEM243
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.32
Red cell distribution width · score 0.24
schizophrenia · score 0.07
autism spectrum disorder · score 0.06
lung carcinoma · score 0.02
cancer · score 0.01
colorectal cancer · score 0.01
non-small cell lung carcinoma · score 0.01
neoplasm · score 0.01
septic shock · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BU79-F1	alphafold	PREDICTED	70.30	—

Amino-acid sequence (118 residues)

MEDFATRTYG TSGLDNRPLF GETSAKDRII NLVVGSLTSL LILVTLISAF VFPQLPPKPL NIFFAVCISL SSITACILIY WYRQGDLEPK FRKLIYYIIF SIIMLCICAN LYFHDVGR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards