Transmembrane protein 70, mitochondrial (TMEM70)

About Transmembrane protein 70, mitochondrial

Transmembrane protein 70, mitochondrial (TMEM70) is a protein from Homo sapiens identified by UniProt accession Q9BUB7, 260 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Transmembrane protein 70, mitochondrial
UniProt accession	Q9BUB7
Gene	TMEM70
Organism	Homo sapiens
Length	260 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BUB7-F1	alphafold	PREDICTED	72.26	—

Amino-acid sequence (260 residues)

MLFLALGSPW AVELPLCGRR TALCAAAALR GPRASVSRAS SSSGPSGPVA GWSTGPSGAA RLLRRPGRAQ IPVYWEGYVR FLNTPSDKSE DGRLIYTGNM ARAVFGVKCF SYSTSLIGLT FLPYIFTQNN AISESVPLPI QIIFYGIMGS FTVITPVLLH FITKGYVIRL YHEATTDTYK AITYNAMLAE TSTVFHQNDV KIPDAKHVFT TFYAKTKSLL VNPVLFPNRE DYIHLMGYDK EEFILYMEET SEEKRHKDDK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards