About Protein PAXX
Protein PAXX (PAXX) is a protein
from Homo sapiens identified by UniProt accession
Q9BUH6, 204 residues long.
MolForge cross-references it against 0 known binders and
88 disease associations.
Target properties
| Protein name | Protein PAXX |
|---|
| UniProt accession | Q9BUH6 |
|---|
| Gene | PAXX |
|---|
| Organism | Homo sapiens |
|---|
| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (88)
Diseases linked to this target (Open Targets).
- lymphocyte percentage of leukocytes · score 0.12
- colon carcinoma · score 0.07
- triple-negative breast cancer · score 0.07
- infection · score 0.07
- infect · score 0.07
- common variable immunodeficiency · score 0.05
- combined immunodeficiency with skin granulomas · score 0.05
- immunodeficiency 75 · score 0.05
- neoplasm · score 0.05
- immunodeficiency 84 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUH6-F1 | alphafold | PREDICTED | 82.87 | — |
Amino-acid sequence (204 residues)
MDPLSPPLCT LPPGPEPPRF VCYCEGEESG EGDRGGFNLY VTDAAELWST CFTPDSLAAL KARFGLSAAE DITPRFRAAC EQQAVALTLQ EDRASLTLSG GPSALAFDLS KVPGPEAAPR LRALTLGLAK RVWSLERRLA AAEETAVSPR KSPRPAGPQL FLPDPDPQRG GPGPGVRRRC PGESLINPGF KSKKPAGGVD FDET
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