Coiled-coil-helix-coiled-coil-helix…

About Coiled-coil-helix-coiled-coil-helix domain-containing protein 7

Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 (CHCHD7) is a protein from Homo sapiens identified by UniProt accession Q9BUK0, 85 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.

Target properties

Protein name	Coiled-coil-helix-coiled-coil-helix domain-containing protein 7
UniProt accession	Q9BUK0
Gene	CHCHD7
Organism	Homo sapiens
Length	85 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (87)

Diseases linked to this target (Open Targets).

Salivary Gland Pleomorphic Adenoma · score 0.37
salivary gland adenoid cystic carcinoma · score 0.37
Salivary Gland Carcinoma ex Pleomorphic Adenoma · score 0.37
Parotid Gland Pleomorphic Adenoma · score 0.37
salivary gland mucoepidermoid carcinoma · score 0.28
body height · score 0.27
forced expiratory volume · score 0.24
lean body mass · score 0.24
appendicular lean mass · score 0.23
vital capacity · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BUK0-F1	alphafold	PREDICTED	84.49	—

Amino-acid sequence (85 residues)

MPSVTQRLRD PDINPCLSES DASTRCLDEN NYDRERCSTY FLRYKNCRRF WNSIVMQRRK NGVKPFMPTA AERDEILRAV GNMPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 (CHCHD7)