About Protein misato homolog 1
Protein misato homolog 1 (MSTO1) is a protein
from Homo sapiens identified by UniProt accession
Q9BUK6, 570 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | Protein misato homolog 1 |
|---|
| UniProt accession | Q9BUK6 |
|---|
| Gene | MSTO1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 570 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome · score 0.82
- Mitochondrial myopathy · score 0.77
- mitochondrial myopathy with reversible cytochrome C oxidase deficiency · score 0.55
- genetic disorder · score 0.38
- mitochondrial disease · score 0.37
- inborn mitochondrial myopathy · score 0.33
- neutrophil count · score 0.24
- urate measurement · score 0.16
- gastric carcinoma · score 0.09
- body mass index · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUK6-F1 | alphafold | PREDICTED | 83.24 | — |
Amino-acid sequence (570 residues)
MAGGAREVLT LQLGHFAGFV GAHWWNQQDA ALGRATDSKE PPGELCPDVL YRTGRTLHGQ ETYTPRLILM DLKGSLSSLK EEGGLYRDKQ LDAAIAWQGK LTTHKEELYP KNPYLQDFLS AEGVLSSDGV WRVKSIPNGK GSSPLPTATT PKPLIPTEAS IRVWSDFLRV HLHPRSICMI QKYNHDGEAG RLEAFGQGES VLKEPKYQEE LEDRLHFYVE ECDYLQGFQI LCDLHDGFSG VGAKAAELLQ DEYSGRGIIT WGLLPGPYHR GEAQRNIYRL LNTAFGLVHL TAHSSLVCPL SLGGSLGLRP EPPVSFPYLH YDATLPFHCS AILATALDTV TVPYRLCSSP VSMVHLADML SFCGKKVVTA GAIIPFPLAP GQSLPDSLMQ FGGATPWTPL SACGEPSGTR CFAQSVVLRG IDRACHTSQL TPGTPPPSAL HACTTGEEIL AQYLQQQQPG VMSSSHLLLT PCRVAPPYPH LFSSCSPPGM VLDGSPKGAA VESIPVFGAL CSSSSLHQTL EALARDLTKL DLRRWASFMD AGVEHDDVAE LLQELQSLAQ CYQGGDSLVD
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