About Ribonuclease P protein subunit p25
Ribonuclease P protein subunit p25 (RPP25) is a protein
from Homo sapiens identified by UniProt accession
Q9BUL9, 199 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Ribonuclease P protein subunit p25 |
|---|
| UniProt accession | Q9BUL9 |
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| Gene | RPP25 |
|---|
| Organism | Homo sapiens |
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| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.11
- alcohol drinking · score 0.11
- low density lipoprotein cholesterol measurement · score 0.09
- red blood cell density measurement · score 0.08
- glioblastoma multiforme · score 0.07
- neutrophil count · score 0.07
- coffee consumption · score 0.07
- smoking status measurement · score 0.07
- diastolic blood pressure · score 0.06
- neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUL9-F1 | alphafold | PREDICTED | 78.81 | — |
Amino-acid sequence (199 residues)
MENFRKVRSE EAPAGCGAEG GGPGSGPFAD LAPGAVHMRV KEGSKIRNLM AFATASMAQP ATRAIVFSGC GRATTKTVTC AEILKRRLAG LHQVTRLRYR SVREVWQSLP PGPTQGQTPG EPAASLSVLK NVPGLAILLS KDALDPRQPG YQPPNPHPGP SSPPAAPASK RSLGEPAAGE GSAKRSQPEP GVADEDQTA
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