About Protein HTATIP2
Protein HTATIP2 (HTATIP2) is a protein
from Homo sapiens identified by UniProt accession
Q9BUP3, 242 residues long.
MolForge cross-references it against 0 known binders and
173 disease associations.
Target properties
| Protein name | Protein HTATIP2 |
|---|
| UniProt accession | Q9BUP3 |
|---|
| Gene | HTATIP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 242 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (173)
Diseases linked to this target (Open Targets).
- fractional shortening · score 0.29
- neoplasm · score 0.11
- FEV change measurement · score 0.11
- response to glucocorticoid · score 0.11
- hepatocellular carcinoma · score 0.11
- non-small cell lung carcinoma · score 0.08
- esophageal squamous cell carcinoma · score 0.08
- tumor predisposition syndrome 2 · score 0.07
- attenuated familial adenomatous polyposis · score 0.07
- Familial adenomatous polyposis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUP3-F1 | alphafold | PREDICTED | 89.17 | — |
Amino-acid sequence (242 residues)
MAETEALSKL REDFRMQNKS VFILGASGET GRVLLKEILE QGLFSKVTLI GRRKLTFDEE AYKNVNQEVV DFEKLDDYAS AFQGHDVGFC CLGTTRGKAG AEGFVRVDRD YVLKSAELAK AGGCKHFNLL SSKGADKSSN FLYLQVKGEV EAKVEELKFD RYSVFRPGVL LCDRQESRPG EWLVRKFFGS LPDSWASGHS VPVVTVVRAM LNNVVRPRDK QMELLENKAI HDLGKAHGSL KP
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