MAPK regulated corepressor interacting protein 2…

About MAPK regulated corepressor interacting protein 2

MAPK regulated corepressor interacting protein 2 (MCRIP2) is a protein from Homo sapiens identified by UniProt accession Q9BUT9, 160 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	MAPK regulated corepressor interacting protein 2
UniProt accession	Q9BUT9
Gene	MCRIP2
Organism	Homo sapiens
Length	160 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

smoking initiation · score 0.03
serum urea measurement · score 0.02
age at first sexual intercourse measurement · score 0.02
Crohn's disease · score 0.01
lung adenocarcinoma · score 0.01
insulin resistance · score 0.01
metabolic disease · score 0.00
myxosarcoma · score 0.00
Cholestasis · score 0.00
pancreatic ductal adenocarcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BUT9-F1	alphafold	PREDICTED	64.30	—

Amino-acid sequence (160 residues)

MYTITKGPSK LVAQRRTGPT QQQVEGRLGE LLKCRQPAPP TSQPPRAQPF AQPPGPWPLS SPGPRLVFNR VNGRRAPSTS PSFEGTQETY TVAHEENVRF VSEAWQQVQQ QLDGGPAGEG GPRPVQYVER TPNPRLQNFV PIDLDEWWAQ QFLARITSCS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

MAPK regulated corepressor interacting protein 2 (MCRIP2)