About EF-hand calcium-binding domain-containing protein 11
EF-hand calcium-binding domain-containing protein 11 (EFCAB11) is a protein
from Homo sapiens identified by UniProt accession
Q9BUY7, 163 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | EF-hand calcium-binding domain-containing protein 11 |
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| UniProt accession | Q9BUY7 |
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| Gene | EFCAB11 |
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| Organism | Homo sapiens |
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| Length | 163 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- Age-related cataract · score 0.19
- drug use measurement · score 0.14
- Epithelioid Cell Uveal Melanoma · score 0.13
- Uveal Melanoma · score 0.12
- colorectal cancer · score 0.01
- hepatocellular carcinoma · score 0.01
- neurodegenerative disease · score 0.00
- renal cell carcinoma · score 0.00
- vulvar intraepithelial neoplasia · score 0.00
- invasive breast ductal carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9BUY7-F1 | alphafold | PREDICTED | 87.36 | — |
Amino-acid sequence (163 residues)
MFFSEARARS RTWEASPSEH RKWVEVFKAC DEDHKGYLSR EDFKTAVVML FGYKPSKIEV DSVMSSINPN TSGILLEGFL NIVRKKKEAQ RYRNEVRHIF TAFDTYYRGF LTLEDFKKAF RQVAPKLPER TVLEVFREVD RDSDGHVSFR DFEYALNYGQ KEA
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