Coiled-coil domain-containing protein 32 (CCDC32)

Homo sapiens — UniProt Q9BV29

Gene: CCDC32Homo sapiensSwissProt reviewed

About Coiled-coil domain-containing protein 32

Coiled-coil domain-containing protein 32 (CCDC32) is a protein from Homo sapiens identified by UniProt accession Q9BV29, 185 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein nameCoiled-coil domain-containing protein 32
UniProt accessionQ9BV29
GeneCCDC32
OrganismHomo sapiens
Length185 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • cardiofacioneurodevelopmental syndrome · score 0.68
  • complex neurodevelopmental disorder · score 0.37
  • mean reticulocyte volume · score 0.12
  • IGF-1 measurement · score 0.12
  • Red cell distribution width · score 0.11
  • blood protein measurement · score 0.09
  • lymphocyte count · score 0.09
  • Abnormality of refraction · score 0.09
  • lymphocyte:monocyte ratio · score 0.07
  • insulin like growth factor measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BV29-F1alphafoldPREDICTED68.74—

Amino-acid sequence (185 residues)

MKMFESADST ATRSGQDLWA EICSCLPNPE QEDGANNAFS DSFVDSCPEG EGQREVADFA VQPAVKPWAP LQDSEVYLAS LEKKLRRIKG LNQEVTSKDM LRTLAQAKKE CWDRFLQEKL ASEFFVDGLD SDESTLEHFK RWLQPDKVAV STEEVQYLIP PESQVEKPVA EDEPAAGDKP AAAEQ

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Quick facts

UniProtQ9BV29
GeneCCDC32
OrganismHomo sapiens
Length185
Binders0
Diseases32
View on UniProt