Vesicle-associated membrane protein 8 (VAMP8)

About Vesicle-associated membrane protein 8

Vesicle-associated membrane protein 8 (VAMP8) is a protein from Homo sapiens identified by UniProt accession Q9BV40, 100 residues long. MolForge cross-references it against 0 known binders and 177 disease associations.

Target properties

Protein name	Vesicle-associated membrane protein 8
UniProt accession	Q9BV40
Gene	VAMP8
Organism	Homo sapiens
Length	100 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (177)

Diseases linked to this target (Open Targets).

coronary artery disease · score 0.33
prostate carcinoma · score 0.33
urinary albumin to creatinine ratio · score 0.32
eosinophil count · score 0.31
myocardial infarction · score 0.30
lean body mass · score 0.29
triglyceride measurement · score 0.28
serum gamma-glutamyl transferase measurement · score 0.28
Myocardial Ischemia · score 0.26
angina pectoris · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BV40-F1	alphafold	PREDICTED	89.88	—

Amino-acid sequence (100 residues)

MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKMIVLI CVIVFIIILF IVLFATGAFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards